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What Is Catatonia?

Catatonia affects motor and behavioural functions and is often linked to mood, psychotic, or medical conditions. In DSM-5, it’s a specifier, not a standalone diagnosis. Understanding what is catatonia helps differentiate it from other movement disorders.

Clinical definition and diagnostic status

Catatonia is included in the DSM-5 as a specifier for conditions like schizophrenia, mood disorders, and even certain medical conditions. It involves a set of motor, behavioural, and autonomic disturbances. It’s important to note that catatonia is not a separate diagnosis like "catatonic schizophrenia," but rather a syndrome that can occur within various psychiatric and medical conditions.

Historical and modern interpretations

Catatonia was once classified as “catatonic schizophrenia,” but understanding has evolved. It’s now recognised as a symptom that can appear across various disorders, including bipolar disorder and depression, reflecting its broader presence in both psychiatric and medical conditions rather than a single diagnosis. Exploring catatonia causes has helped reshape this understanding in modern psychiatry.

Types of catatonia

There are three main types of catatonia:

Retarded catatonia: Characterised by slowed movements, immobility, and a lack of responsiveness.
Excited catatonia: Involves excessive agitation, hyperactivity, and impulsivity.
Malignant catatonia: The most severe form, which can cause life-threatening catatonia symptoms such as fever, rigidity, and autonomic instability.
Understanding the catatonia types is crucial to developing effective care plans and interventions based on severity and presentation.
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Common Symptoms of Catatonia 

Catatonia presents through a wide range of symptoms, which can include motor, behavioural, and autonomic changes. It may vary in severity, from mild disturbances to life-threatening situations, and can significantly impact an individual’s daily functioning. These varying signs of catatonia highlight the importance of early identification.

Motor symptoms 

Motor catatonia symptoms are some of the most prominent and can include: 

  • Immobility: Complete stillness and unresponsiveness to surroundings.  
  • Waxy Flexibility: Limbs stay in place positions when moved.  
  • Posturing: Holding unusual poses for extended periods.  
  • Negativism: Resisting movement or instructions.  

These symptoms range in severity and impair normal functioning. 

Behavioural symptoms 

Catatonia also affects a person’s behaviour in significant ways. Common behavioural catatonia symptoms include: 

  • Mutism: No verbal communication despite the ability to speak. 
  • Echolalia: Repeating others’ words. 
  • Echopraxia: Copying others’ movements. 
  • Extreme Withdrawal: Avoiding interaction and isolating from surroundings. 

These behaviours make communication and care challenging for families and healthcare providers. 

Autonomic or life-threatening signs 

In more severe cases of catatonia, particularly in malignant catatonia, the condition can lead to life-threatening symptoms, such as: 

  • Fever: Dangerously high temperature. 
  • High Blood Pressure: Can trigger serious health issues. 
  • Rigidity: Severe muscle stiffness affecting breathing and organs. 
  • Malignant catatonia is a medical emergency and can be fatal without urgent treatment. 

Catatonia treatment in such cases must be immediate to avoid complications.

Causes and Risk Factors of Catatonia 

Catatonia causes stems from a mix of biological, psychological, and social factors. Often linked to psychiatric, medical, or substance-related causes, early recognition improves catatonia treatment and recovery outcomes. 

Underlying psychiatric disorders 

Psychiatric disorders are key triggers for catatonia. Schizophrenia, bipolar disorder, and major depression can cause motor and behavioural symptoms.  

In bipolar episodes or schizophrenia, disorganised thinking and emotional instability often manifest as catatonia, with severity and type of illness influencing its onset. 

Medical/neurological causes 

Medical and neurological catatonia causes include autoimmune encephalitis, metabolic imbalances (e.g., sodium or calcium), and severe brain infections that can trigger catatonia. These disrupt brain function and may lead to psychiatric symptoms.  

Early diagnosis and treatment are essential to manage these underlying causes and prevent serious complications. 

Substance-induced or withdrawal-related causes 

Substance use and withdrawal can also lead to catatonia. Benzodiazepine withdrawal is a common cause, as the body experiences severe reactions when discontinuing these medications.  

Additionally, some antipsychotic medications can induce catatonia as a side effect. The interaction between substances and the brain’s chemistry can result in significant motor and behavioural disturbances. 

Complications and Risks of Untreated Catatonia 

If left untreated, catatonia can lead to significant physical and psychological complications. Recognising the dangers of untreated catatonia is crucial for improving individuals’ outcomes and preventing long-term damage. 

Risk of physical complications 

Untreated catatonia can lead to severe complications like muscle breakdown (rhabdomyolysis), blood clots (DVT), and aspiration (food or liquid entering the lungs). These risks can cause kidney damage, lung issues, or life-threatening conditions, requiring urgent medical intervention. 

Mental health deterioration 

Untreated catatonia can worsen mental health, increasing psychosis, intensifying depression, and heightening suicidal risk. The lack of intervention may deepen feelings of isolation and hopelessness. Early treatment is crucial to prevent further psychological deterioration and reduce these risks. 

Risk of mortality in malignant catatonia 

Malignant catatonia is a life-threatening form of the condition and requires urgent medical attention. Symptoms such as fever, rigidity, and autonomic instability can quickly escalate to a crisis point.  Recognising these early signs of catatonia is crucial for treatment.

If not treated promptly, malignant catatonia can lead to severe complications, including organ failure and death. Immediate care is essential to prevent fatal outcomes. 

Diagnosis of Catatonia 

Diagnosing catatonia requires a careful and systematic approach. Clinicians typically follow a set of steps to evaluate the symptoms and identify the underlying causes. 

Clinical observation and rating scales 

Clinicians often rely on clinical observation and rating scales to assess the presence of catatonia. The Bush-Francis Catatonia Rating Scale (BFCRS) is one of the most widely used tools to evaluate the severity of catatonic symptoms.  

Additionally, the DSM-5 checklist helps doctors identify the characteristic symptoms of catatonia, such as immobility, posturing, and mutism. 

Neurological and medical evaluation 

To ensure an accurate diagnosis, healthcare providers conduct a thorough neurological and medical evaluation. This process helps rule out other conditions that may mimic catatonia, such as seizures, infections, or metabolic disorders.  

Blood tests, brain imaging, and other diagnostic tools may be used to determine the cause of the catatonic symptoms. 

Differential diagnosis 

Catatonia must be distinguished from conditions like neuroleptic malignant syndrome (NMS), akinetic mutism, and Parkinsonism, which share similar symptoms. Accurate diagnosis, based on patient history, symptoms, and tests, is crucial for effective treatment and differentiating these conditions. 

Effective Treatment Options for Catatonia 

Catatonia is treatable with timely intervention. Treatment aims to relieve symptoms and address underlying causes through medications, therapies, and supportive care, tailored to the severity and specific condition. 

Benzodiazepines (e.g., lorazepam challenge test) 

Benzodiazepines, like lorazepam, are often the first-line treatment for catatonia. The lorazepam challenge test involves administering a small dose to observe rapid symptom improvement.  

If symptoms improve, it confirms the diagnosis, allowing for continued benzodiazepine treatment to effectively alleviate motor and behavioural symptoms. 

Electroconvulsive Therapy (ECT) 

Electroconvulsive therapy (ECT) is highly effective for treating catatonia, especially in severe or resistant cases. It is typically used when benzodiazepines fail to provide relief or in cases of malignant catatonia.  

ECT can rapidly improve symptoms and is considered a safe and effective option for long-term recovery. 

Managing underlying psychiatric disorder 

Treating the underlying psychiatric disorder is crucial in managing catatonia. Conditions like schizophrenia, bipolar disorder, or severe depression can trigger catatonic symptoms.  

Addressing these disorders through medication, therapy, or both helps reduce the recurrence of catatonia and provides long-term stability for the individuals’ mental health. 

Supportive care and monitoring 

Supportive care plays a vital role in managing catatonia. This includes ensuring proper nutrition, hydration, and monitoring for potential complications such as muscle breakdown or blood clots.  

Close observation and ongoing care help prevent further physical health issues, promoting recovery alongside primary treatment for the condition. 

When to Seek Emergency Help 

Catatonia can quickly worsen, so recognising when to seek urgent medical attention is critical. There are specific signs and symptoms that indicate the need for immediate intervention. 

Signs of malignant catatonia 

Malignant catatonia is a severe and life-threatening form of the condition. If you notice any of the following symptoms, seek emergency medical care immediately: 

  • High fever 
  • Muscle rigidity 
  • Confusion 
  • Autonomic instability (unstable blood pressure, heart rate changes) 

These symptoms can quickly lead to organ failure and other serious complications, making urgent care essential. 

Rapid deterioration in functioning 

If someone with catatonia experiences a rapid deterioration in functioning, such as an inability to eat, speak, or move safely, it’s crucial to seek emergency help.  

These changes indicate that the condition is progressing rapidly and may lead to severe physical and psychological consequences if not addressed immediately. 

Why Choose Cadabam’s Hospital for Catatonia Treatment? 

At Cadabam’s Hospital, we provide expert care for catatonia, offering tailored treatment plans through a multidisciplinary team of psychiatrists, psychologists, and medical professionals.  

With advanced diagnostics, treatments like ECT, and compassionate care, we ensure the best outcomes for each individual. Our expertise in both psychiatric and medical aspects makes us a trusted choice for those seeking specialised care. 

If you are searching for a solution to your problem, Cadabam’s Hospitals can help you with its team of specialised experts. We have been helping thousands of people live healthier and happier lives for 30+ years. We leverage evidence-based approaches and holistic treatment methods to help individuals effectively manage their catatonia. Get in touch with us today. You can call us at +91 97414 76476. You can even email us at info@cadabamshospitals.com.

FAQs 

Is catatonia the same as schizophrenia? 

No, catatonia is not the same as schizophrenia. While it can occur in schizophrenia, catatonia is a distinct condition characterised by motor and behavioural disturbances, and it can also occur in other psychiatric or medical conditions. 

Is catatonia treatable? 

Yes, catatonia is treatable. Medications like benzodiazepines and therapies such as Electroconvulsive Therapy (ECT) are commonly used to manage symptoms. Treatment is effective, especially when administered early, and can significantly reduce or reverse symptoms. 

How fast does catatonia respond to treatment? 

Catatonia often responds quickly to treatment, particularly with benzodiazepines like lorazepam. Many individuals show significant improvement within hours or days, especially with prompt intervention. Malignant catatonia may take longer and require more intensive treatment, like ECT. 

Can catatonia be fatal? 

Yes, catatonia can be fatal, particularly in its malignant form. If left untreated, it can lead to serious complications such as organ failure, muscle breakdown, or aspiration pneumonia, which can be life-threatening and require urgent medical care.

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